CTSI welcomes new trainees and scholars

Person showing welcomeThe CTSI welcomes the following scholars and trainees that will begin their funded projects on July 1:

KL2 Scholars

Beau Abar, PhD (Mentor: Manish Shah, MD)
“Enhancing patient access to appropriate medical care across the lifespan, with a particular emphasis on access to substance abuse and other psychiatric treatment”

Suzannah Iadarola, PhD (Mentor: Tristram Smith, PhD)
“Mindfulness-Based Intervention for Parents of Children with Autism Spectrum Disorders”

Megan Lytle, PhD (Mentor: Vincent Silenzio, MD, MPH)
“Lesbian, gay, bisexual, and transgender (LGBT) health disparities/suicide prevention”

CTSI Year Out Trainees

Josef Bartels (Mentor: Ronald Epstein, MD)
“The Qualities of Science”

Michael Geary (Mentor: Regis O’Keefe, MD, PhD)
“Modulation of the prostanoid receptor EP4 to reduce scarring during flexor tendon healing”

Trevor Hansen (Mentor: Howard Langstein, MD)
“Thy1 Expression as a Marker and Therapeutic Target for Scar Formation in Capsular Contracture Following Reconstruction Mammoplasty”

Kelly Makino (Mentor: Anton Porsteinsson, MD)
“Advance Care Planning in Early Dementia Study”

Kyle Rodenbach (Mentor: George Schwartz, MD)
“Cystatin-C-based renal reserve in children with history of hemolytic uremic syndrome-associated acute kidney injury”

Lauren Roussel (Mentor: Howard Langstein, MD)
“Evaluating Upper Extremity Function Following Mastectomy in Reconstructed and Non-Reconstructed Women with Breast Cancer”

Elizabeth Saionz (Mentor: Jeff Bazarian, MD, MPH)
“Post-concussion progesterone decline in female athletes”

Lindsay Wahl (Mentor: Patricia Sime, MD)
“One Protein, Multiple Functions: The Role of Tissue Transglutaminase in Pulmonary Fibrosis”

To learn more about the CTSI Year Out program, click here. To learn more about the KL2 program, click here.

CTSI Seminar Series: CTSI Year Out Trainee Presentations Part II

presentations1-241x262The CTSI Seminar Series for Spring 2014 continues on Tuesday, April 22nd with a presentation by two CTSI Year Out Trainees. The CTSI supports medical students interested in a year-out experience of mentored research in clinical or translational research. The following two trainees will be presenting their research:

Aimee Morris – “Clinical Characteristics, Musical Variables, and Pathophysiology of Focal Embouchure Dystonia: A Disabling Disorder of Musicians”

Jeffrey Reed - “The Effects of Erythropoietin on Healthy Bone

The learn more about the CTSI Year Out program, click here.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CTSI Seminar Series: CTSI Year Out Trainee Presentations Part I

presentations1-241x262The CTSI Seminar Series for Spring 2014 continues on Tuesday, April 15th with a presentation by three CTSI Year Out Trainees. The CTSI supports medical students interested in a year-out experience of mentored research in clinical or translational research. The following three trainees will be presenting their research:

David Paul – “Using DTI to measure changes in occipital lobe white matter after decompression of the optic chiasm”

Jarrod Bogue – “Investigation of the fundamental biochemistry and conformational properties of a specific riboswitch from Neisseria gonorrhoeae”

Melissa Squires – “Analysis of Inpatient Data on Patients with Intellectual and Developmental Disabilities at Strong Memorial Hospital”

The learn more about the CTSI Year Out program, click here.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CTSI Seminar Series: Mobile phone-based asthma self-management aid for adolescents (mASMAA): “Txt4ASMA”

textingThe CTSI Seminar Series for Spring 2014 continues on Tuesday,April 8th with a presentation by Hyekrun Rhee, PhD, RN, PNP and James Allen, PhD. Drs. Rhee and Allen will be presenting their research in a seminar entitled “Mobile phone-based asthma self-management aid for adolescents (mASMAA): Txt4ASMA.” Dr. Rhee is an Associate Professor at the School of Nursing and Dr. Allen is the John H. Dessauer Professor of Computer Science on River Campus.

Abstract: Adolescents report high asthma-related morbidity that can be prevented by adequate self-management of the disease. Therefore, there is a need for a developmentally appropriate strategy to promote effective asthma self-management. Mobile phone-based technology is portable, commonly accessible, and well received by adolescents. The purpose of this study was to develop and evaluate the feasibility and acceptability of a comprehensive mobile phone-based asthma self-management aid for adolescents (mASMAA) that was designed to facilitate symptom monitoring, treatment adherence, and adolescent–parent partnership. The system used state-of-the-art natural language-understanding technology that allowed teens to use unconstrained English in their texts, and to self-initiate interactions with the system.

Drs. Rhee and Allen published their findings in the journal “Patient Preference and Adherence.” To read the entire publication, click here.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CTSI Seminar Series: When Erythrocyte Biology and Mechanics Collide

RedBloodCells3The CTSI Seminar Series for Spring 2014 continues on Tuesday, April 1st with a presentation by Richard Waugh, PhD and James Palis, MD. Drs. Waugh and Palis will be presenting their research in a seminar entitled “When Erythrocyte Biology and Mechanics Collide.”

(UPDATE: For a recap of the presentation, click here.)

Dr. Palis is a Professor in the Department of Pediatrics, Hematology and Oncology at the Medical Center and Dr. Waugh is Chair and Professor in the Department of Biomedical Engineering on River Campus. Dr. Palis and Dr. Waugh are Co-Principal Investigators on a CTSI Incubator award with Michael Bulger, PhD titled “Extensively Self-Renewing Erythroblasts as an Ex-Vivo Source of Human Blood.” In response to the increased blood transfusion need in the United States, their project will explore ways to artificially generate human blood. Click here to read more about their project.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CTSI Education Spotlight: David Paul, ART Student

david paulAs a child, I always dreamed of pursuing a career that would combine my interests in science, engineering, business and the arts. After reading the book, Gifted Hands, by Dr. Ben Carson, a Johns Hopkins, neurosurgeon, I knew that medicine would fulfill my interests and allow me to make a lasting impact on my community. Driven to one-day be a physician, I went on to continue my education at Hope College, in Holland, MI; obtaining a B.S. in chemistry. During my time as an undergraduate, I conducted biophysics research in the laboratory of Dr. Brent P. Kreuger at Hope College and was awarded a Cyberinfrastructure Experiences for Graduate Students (NIH-CIEG) Fellowship to study under Dr. Ross Walker at the San Diego Supercomputer Center – University of California, San Diego.

In 2010, I was accepted into the MD program at the University of Rochester School of Medicine and Dentistry. During my first two years of medical school I became increasingly fascinated with the human brain; wanting to know more about it’s function after injury. This prompted a summer research project within the Departments of Neurosurgery, and Brain and Cognitive Sciences at the University of Rochester; where we used anatomical and functional magnetic resonance imagining to characterize the trajectory of visual recovery and cortical plasticity after surgical tumor resection in patients with pituitary tumors that compress the optic nerves. My background in computational methods and biophysics research prepared me to analyze complex neuroimaging data under the supervision of Drs. Bradford Mahon, PhD and G. Edward Vates, MD PhD.

After spending a summer in Dr. Mahon’s lab and shadowing Dr. Vates, a URMC neurosurgeon, my eyes were opened to the plethora of questions that remain unanswered concerning vision loss in pituitary tumor patients. Funding from the CTSI and support from the Academic Research Track Fellowship, in conjunction with the Academic Honors Program in Medical Neurobiology, provided me with an opportunity to answer these question through a dedicated 2-year research fellowship. This spring I will graduate with a masters in Neurobiology and Anatomy and begin the clinical years of my medical education. I am truly grateful to the CTSI for their support of my dreams.

CTSI Seminar Series: Listening through noise: Search for Autism biomarkers

Autism_Awareness_RibbonThe CTSI Seminar Series for Spring 2014 continues on Tuesday, March 25th with a presentation by Anne Luebke, PhD and Loisa Bennetto, PhD. Drs. Luebke and Bennetto will be presenting their research in a seminar entitled “Listening through noise: Search for Autism biomarkers.” Dr. Luebke is an Associate Professor in the Departments of Biomedical Engineering and Neurobiology and Anatomy at the Medical Center. Dr. Bennetto is Chair and Associate Professor in the Department of Psychology on River Campus. The research done in the Bennetto Lab is broadly directed at examining the neurocognitive bases of developmental disabilities, with the ultimate goal of understanding how atypical neurocognitive development relates to deficits in social-communication functioning as well as everyday difficulties with adaptive functioning. The goal of the Luebke lab is to understand the role of cochlear outer hair cells in hearing and hearing loss both at the molecular and at the systems level. Specifically, they are interested in agents that block or enhance the action of receptors on outer hair cells of the cochlea, which enhance hearing and decrease hearing loss.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CTSI Seminar Series: Progress toward noninvasive vision correction

knox huxlinThe CTSI Seminar Series for Spring 2014 continues on Tuesday, March 18th with a presentation by Krysten Huxlin, PhD and Wayne Knox, PhD. Drs. Huxlin and Knox will be presenting their research in a seminar entitled “Progress toward noninvasive vision correction.” Dr. Huxlin is Professor in the Departments of Ophthalmology, Neurobiology & Anatomy, Brian & Cognitive Sciences and the Center for Visual Science. Dr. Knox is the Associate Dean of Education and New Initiatives and Professor in the Departments of Optics and Physics and Visual Sciences. Click here to learn more about their research collaboration.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Summer course for PhD students interested in clinical and translational research

Rochester GroupThe NIH Clinical Center invites graduate students to apply to the Clinical and Translational Research Course for Ph.D. Students, to be held at the NIH main campus in Bethesda, MD July 7-18, 2014. During the two-week intensive course, students will learn the process of clinical and translational research from concept to implementation. This training is offered by the Clinical Center at no cost. Participants are responsible for their travel and housing. Application deadline is April 1, 2014. For additional information, please call (301) 435-8015 or visit http://cc.nih.gov/training/phdcourse.

Last year, 4 PhD students from the University of Rochester attended the course; Amanda Croasdell, Katie Lanin, Marina Feigenson and HsiMin Hsiao.  Some of those students describe their experience below:

Amanda Croasdell:
It was really incredible to learn about the programs involved in one of NIH’s newest divisions, NCATS. Not only is this division doing cutting edge research, they are also working to improve toxicology techniques and increase collaborative research efforts. I have been considering work at the NIH as a potential career path, and this course definitely increased my interest! It was inspiring to see the research opportunities available and to experience the collaborative and supportive research system first hand.

Katie Lanin:
The two week NIH course was a great opportunity to network with clinical researchers in my field at the NIH clinical center.  This intensive course focused mainly on clinical trial design, procedures, and analysis.  We participated in workshops and attended seminars highlighting cutting edge research at the NIH.  One day of the course was spent at the FDA, learning about regulatory science and the process required to approve a drug or device for clinical use.  This was of particular interest to me and provided the opportunity to learn about postdoctoral positions at the NIH and FDA.  This course certainly enhanced my knowledge of clinical translational sciences and helped to shape my research and career path.  I would highly recommend this course to any student who is interested in clinical translational research or postdoctoral positions at the NIH.

HsiMin Hsiao:
First we were able to get insight of what NIH has been focusing and its central mission. We are able to appreciate NIH as a “leading research institute”, rather than a “funding agency”. By attending to different modules, we were able to learn to carry our research from the benchside to bedside, which is apparently a core value of this course. At the end, it is especially beneficial to students like me who is seeking a career opportunity given that NIH has variety of fellowship programs that we might interested in. Overall we had great experience at the NIH, and will definitely recommend people who are planning to go this year to prepare ahead of the deadline. Due to the growing popularity of this course, they are expecting significantly more applicants this year than previous two years!

CTSI Seminar Series: Using MRI to predict visual recovery after tumor resection

MRIThe CTSI Seminar Series for Spring 2014 continues on Tuesday, March 11th with a presentation by Brad Mahon, PhD. Dr. Mahon will be presenting on a research collaboration with G. Edward Vates, MD, PhD in a seminar entitled “Using MRI to predict visual recovery after tumor resection.” Dr. Mahon works in the Concepts, Actions and Objects (CAO) Lab and his research addresses the processes involved in categorization and recognition of the visual input, the engagement of motor knowledge necessary to manipulate objects, and the dynamics of information retrieval within the speech production system.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.