CTSI Seminar Series: Nanoparticle-mediated gene silencing confers radio protection to salivary glands in vivo

gene silencingThe CTSI Seminar Series for Spring 2014 continues on Tuesday, February 4th with a presentation by Stephen Dewhurst, PhD; Danielle Benoit, PhD; and Catherine Ovitt, PhD. Drs. Dewhurst, Benoit and Ovitt will be presenting their research in a seminar entitled “Nanoparticle-mediated gene silencing confers radio protection to salivary glands in vivo.” Nanoparticles were formulated to provide siRNA delivery to salivary glands. Introduction of siRNA against proapoptotic genes was demonstrated in vitro and in vivo to protect glands against radiation damage. This is a collaboration between the Benoit and Ovitt labs. They will also discuss some new and different directions of our collaboration that involves tissue engineering approaches.

The theme of the Spring 2014 series is “Crossing Elmwood: River Campus-Medical Center Research Collaborations” and will showcase ongoing research collaborations between the University research community and the Medical Center. The series also aims to stimulate new research teams and areas of investigation capitalizing on the existing strength of faculty and programs. The Organizing Committee for the series includes Robert Holloway, MD, MPH, Peter Lennie, PhD, Rob Clark, PhD, Stephen Dewhurst, PhD, Karl Kieburtz, MD, MPH, David Williams, PhD, Richard Waugh, PhD,  and Joanna Olmsted, PhD.

The series takes place on Tuesdays from 12:15-1:15 pm in the Helen Wood Hall Auditorium. You can access the full schedule here. Lunch is provided. Please provide your own beverage. The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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